Early syphilis in Guangzhou, China: presentation, molecular detection of Treponema pallidum , and genomic sequences in clinical specimens and isolates obtained by rabbit infectivity testing.
Ligang YangXiaohui ZhangWentao ChenArlene C SeñaHeping ZhengYinbo JiangPeizhen ZhaoRongyi ChenLiuyuan WangWujian KeJuan C SalazarJonathan B ParrJoseph D TuckerKelly L HawleyMelissa J CaimanoChristopher M HennellyFarhang AghakanianFeifei ZhangJane S ChenM Anthony MoodyJustin D RadolfBin YangPublished in: medRxiv : the preprint server for health sciences (2023)
molecular detection and genome sequencing from multiple specimens collected from early syphilis patients and isolates obtained by rabbit inoculation. Our results support the use of whole genome sequencing from rabbit isolates to inform syphilis vaccine development.