Is the presence of tumor-infiltrating lymphocytes predictive of outcomes in patients with melanoma?
Steven L MorrisonGang HanFaith ElenwaJohn T VettoGraham FowlerStanley P LeongMohammed Kashani-SabetBarbara A PockajHeidi E KosiorekJonathan S ZagerVernon K SondakJane L MessinaNicola MozzilloSchlomo SchneebaumDale Hannull nullPublished in: Cancer (2022)
TILs are a favorable marker because their presence significantly predicts a negative SLN, and the absence of TILs may be a prognostic marker of worse survival in patients with a positive SLN but not a negative SLN. TILs may also serve as a prognostic marker of survival when the SLN status is not considered.