Combined genetic analysis of juvenile idiopathic arthritis clinical subtypes identifies novel risk loci, target genes and key regulatory mechanisms.
Elena López-IsacSamantha Louise SmithMiranda C MarionAbigail WoodMarc SudmanAnnie YarwoodChenfu ShiVasanthi Priyadarshini GaddiPaul MartinSampath PrahaladStephen EyreGisela OrozcoAndrew P MorrisCarl D LangefeldSusan D ThompsonWendy ThomsonJohn David BowesPublished in: Annals of the rheumatic diseases (2020)
In a large JIA GWAS, we identify five novel risk loci and describe potential function of JIA association signals that will be informative for future experimental works and therapeutic strategies.