Palladium-Catalyzed Oxidative Cyclization of α-Allenols in the Presence of TBN: Access to 3(2 H )-Furanones.
Ganesh S GhotekarRavi A ShindeSagar S SaswadeM MuthukrishnanPublished in: The Journal of organic chemistry (2023)
A new palladium-catalyzed oxidative cyclization of α-allenols is described. The readily accessible α-allenols participate in intra-molecular oxidative cyclization in the presence of TBN to grant access to multisubstituted 3(2 H )-furanones, which are common motifs in several biologically important natural products and pharmaceuticals.
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