Synthesis of [ 18 F]FMISO, a hypoxia-specific imaging probe for PET, an overview from a radiochemist's perspective.

Torsten KniessJörg ZessinPeter MädingManuela Kuchar Oliver C Neels Klaus Kopka

Published in: EJNMMI radiopharmacy and chemistry (2023)

F]FMISO, based on in-house prepared FASTlab cassettes, providing the radiotracer for research and preclinical purposes in good radiochemical yields (39%), high radiochemical purities (> 99%) and high molar activity (> 500 GBq/µmol) in a well-priced option.

Keyphrases

pet imaging
computed tomography
pet ct
positron emission tomography
stem cells
quantum dots
cell therapy
living cells
mesenchymal stem cells
fluorescence imaging