Association Between Indoxyl Sulfate and Dialysis Initiation and Cardiac Outcomes in Chronic Kidney Disease Patients.
Kullaya TakkavatakarnJeerath PhannajitSuwasin UdomkarnjananunSuri TangchitthavorngulPajaree ChariyavilaskulPatita SitticharoenchaiKearkiat PraditpornsilpaSomchai Eiam-OngPaweena SusantitaphongPublished in: International journal of nephrology and renovascular disease (2022)
Serum indoxyl sulfate level was a significant predictor for CKD progression to dialysis and was correlated with GLS, a speckle tracking echocardiography parameter representing early LV systolic dysfunction. Furthermore, GLS was associated with cardiovascular events in CKD patients. Serum indoxyl sulfate measurement may help to identify the high dialysis and cardiovascular risk CKD patients beyond traditional risk factors.
Keyphrases
- end stage renal disease
- chronic kidney disease
- peritoneal dialysis
- cardiovascular events
- newly diagnosed
- ejection fraction
- risk factors
- left ventricular
- heart failure
- blood pressure
- cardiovascular disease
- adipose tissue
- coronary artery disease
- type diabetes
- metabolic syndrome
- atrial fibrillation
- pulmonary hypertension
- insulin resistance