A polygenic score for age-at-first-birth predicts disinhibition.

Leah S Richmond-RakerdTerrie E MoffittLouise ArseneaultDaniel W BelskyJennie ConnorDavid L CorcoranHonaLee HarringtonRenate M HoutsRichie PoultonJoey A PrinzSandhya RamrakhaKaren SugdenJasmin WertzBenjamin S WilliamsAvshalom Caspi

Published in: Journal of child psychology and psychiatry, and allied disciplines (2020)

Genomic discoveries for age-at-first-birth are about more than reproductive biology: They provide insight into the disinhibitory traits and behaviors that accompany early parenthood. Age-at-first-birth is a useful proxy phenotype for researchers interested in disinhibition. Further, interventions that improve self-regulation abilities may benefit young parents and their children.

Keyphrases

gestational age
young adults
physical activity
genome wide
pregnancy outcomes
gene expression
pregnant women
copy number