Genetic evidence for efficacy of targeting IL-2, IL-6 and TYK2 signalling in the prevention of type 1 diabetes: a Mendelian randomisation study.

Tea E Heikkilä Emilia K Kaiser Jake Lin Dipender Gill Jaakko J Koskenniemi Ville Karhunen

Published in: Diabetologia (2024)

The analysis code is available at https://github.com/jkoskenniemi/T1DSCREEN , which also includes instructions on how to download the original GWAS summary statistics.

Keyphrases

genome wide
gene expression
copy number
drug delivery