Polyphenolic extracts from Diospyros kaki and Vitis vinifera by-products stimulate cytoprotective effects in bacteria-cell host interactions by mediation of transcription factor Nrf2.

Bryan Moreno-ChambaJulio Salazar-BermeoMarta Narváez-AsensioPablo Navarro-SimarroDomingo SauraMadalina NeacsuNuria MartíManuel ValeroMaría Concepción Martínez-Madrid

Published in: Phytomedicine : international journal of phytotherapy and phytopharmacology (2024)

Our results highlight the therapeutic potential of GrPE, PePE, and PoPE in shaping bacterial-host interactions, endorsing their utility as novel nutraceuticals for both oral and topical applications to prevent potential bacterial infections through innovative mechanisms.

Keyphrases

transcription factor
single cell
oxidative stress
cell therapy
dna binding
human health