A randomized split-scalp study comparing calcipotriol-assisted methyl aminolaevulinate photodynamic therapy (MAL-PDT) with conventional MAL-PDT for the treatment of actinic keratosis.

Luis Antonio TorezanB GrinblatM HaedersdalN ValenteC Festa-NetoR M Szeimies

Published in: The British journal of dermatology (2018)

CAL-assisted PDT proved to be safe and more effective than conventional MAL-PDT for the treatment of AKs on the scalp. CAL pretreatment increased PpIX accumulation within the skin and may have enhanced the efficacy in this first human trial.

Keyphrases

photodynamic therapy
fluorescence imaging
endothelial cells
clinical trial
phase iii