The role of comprehensive analysis with circulating tumor DNA in advanced non-small cell lung cancer patients considered for osimertinib treatment.
Naoko Sueoka-AraganeChiho NakashimaHironori YoshidaNaohisa MatsumotoKentaro IwanagaNoriyuki EbiAkihiro NishiyamaKazuhiro YateraShoichi KuyamaMinoru FukudaSunao UshijimaHitomi UmeguchiDaijiro HaradaKosuke KashiwabaraTakayuki SuetsuguNobukazu FujimotoFumihiro TanakaHidetaka UramotoChiharu YoshiiKatsumi NakatomiGenju KohNobuhiko SekiKeisuke AoeKaname NosakiKoji InoueAyako TakamoriAtsushi KawaguchiPublished in: Cancer medicine (2021)
NGS of ctDNA could be a promising method for predicting osimertinib efficacy in patients with advanced NSCLC harboring EGFR T790 M.