MIR-203A-3P AND MMP-2 PROTEINS ARE HIGHLY EXPRESSED IN CIRCULATING TUMOR CELLS FROM PATIENTS WITH PANCREATIC CARCINOMA.

José Gabriel Rodríguez Tarazona Emne Ali Abdallah Bianca de Cássia Troncarelli Flores Alexcia Camila Braun Cláudia Malheiros Coutinho Camillo Fabio Albuquerque Marchi Anna Paula Carreta Ruano Ludmilla Thomé Domingos Chinen

Published in: Arquivos brasileiros de cirurgia digestiva : ABCD = Brazilian archives of digestive surgery (2022)

Due to the low number of patients and short follow-up, we did not observe a correlation between CTCs and response to treatment. However, there was a correlation between CTM and DVT and also miR-203a-3p was highly expressed in CTCs, corroborating the findings of EMT proteins. This study opens the perspectives concerning the dynamic change in the pattern of proteins expressed along with treatment and the use of miRNAs as new targets in pancreatic carcinoma.

Keyphrases

circulating tumor cells
end stage renal disease
newly diagnosed
chronic kidney disease
ejection fraction
peritoneal dialysis
patient reported outcomes
cell migration