High-dose opioid utilization and mortality among individuals initiating hemodialysis.

Matthew DaubresseG Caleb AlexanderDeidra C CrewsDorry L SegevKrista L LentineMara Ann McAdams-DeMarco

Published in: BMC nephrology (2021)

The risk of mortality associated with opioid utilization among individuals on hemodialysis increases as doses exceed 60MME per day and is greatest during periods of high-dose utilization. Patients and clinicians should carefully weigh the risks and benefits of opioid doses exceeding 60MME per day.

Keyphrases

high dose
end stage renal disease
chronic kidney disease
peritoneal dialysis
chronic pain
pain management
low dose
cardiovascular events
stem cell transplantation
newly diagnosed
ejection fraction
risk factors
palliative care
type diabetes
human health
patient reported outcomes