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Sympathetic activation by lower body negative pressure decreases kidney perfusion without inducing hypoxia in healthy humans.

René van der BelJasper VerbreeOliver J Gurney-ChampionMatthias J P van OschErik S G StroesAart Johannes NederveenC T Paul Krediet
Published in: Clinical autonomic research : official journal of the Clinical Autonomic Research Society (2018)
The results suggest that an increase in sympathetic vasoconstrictor drive decreases kidney perfusion without a parallel reduction in oxygenation in healthy humans. This in turn indicates that sympathetic activation suppresses renal oxygen demand and supply equally, thus allowing adequate tissue oxygenation to be maintained.
Keyphrases
  • contrast enhanced
  • blood flow
  • signaling pathway
  • sensitive detection
  • magnetic resonance
  • living cells