Ability of procalcitonin to distinguish between bacterial and nonbacterial infection in severe acute exacerbation of chronic obstructive pulmonary syndrome in the ICU.

Cédric DaubinFrançois FournelFabrice ThiollièreFabrice DaviaudMichel RamakersAndréa PolitoBernard FlocardXavier ValetteDamien Du CheyronNicolas TerziMuriel FartoukhStephane AlloucheJean-Jacques Parientinull null

Published in: Annals of intensive care (2021)

Despite higher PCT levels in severe AECOPD caused by bacterial infection, PCT had a poor accuracy to distinguish between bacterial and nonbacterial infection. Procalcitonin might not be sufficient as a standalone marker for initiating antibiotic treatment in this setting.

Keyphrases

chronic obstructive pulmonary disease
intensive care unit
pulmonary hypertension
early onset
combination therapy
extracorporeal membrane oxygenation
replacement therapy