Opportunistic yeast pathogen Candida spp.: Secreted and membrane-bound virulence factors.
Si Jie LimMohd Shukuri Mohamad AliSuriana SabriNoor Dina Muhd NoorAbu Bakar SallehSiti Nurbaya OslanPublished in: Medical mycology (2022)
Candida virulence factors (VFs) including mainly enzymes and proteins play vital roles in breaching the human intestinal barrier and causing deadly invasive candidiasis. Limited VFs' structural studies hinder deeper comprehension of their mechanisms and thus the design of vaccines and antifungal drugs against fungal infections.