Mitochondrial Generated Redox Stress Differently Affects the Endoplasmic Reticulum of Circulating Lymphocytes and Monocytes in Treatment-Naïve Hodgkin's Lymphoma.
Cecilia MariniVanessa CossuMatteo BaucknehtSonia CartaFrancesco LanfranchiFrancesca D'AmicoSilvia RaveraAnna Maria OrengoChiara GhiggiFilippo BalleriniPaolo DurandoSabrina ChiesaAlberto MiceliMaria Isabella DoneganiSilvia MorbelliSilvia BrunoGianmario SambucetiPublished in: Antioxidants (Basel, Switzerland) (2022)
PBMCs of HL patients display a selective mitochondrial and ER redox stress most evident in lymphocytes already before the exposure to chemotherapy toxicity.
Keyphrases
- endoplasmic reticulum
- oxidative stress
- peripheral blood
- end stage renal disease
- ejection fraction
- newly diagnosed
- chronic kidney disease
- prognostic factors
- dendritic cells
- immune response
- locally advanced
- patient reported outcomes
- radiation therapy
- combination therapy
- breast cancer cells
- heat stress
- replacement therapy
- patient reported