Login / Signup

Using DNA From Mothers and Children to Study Parental Investment in Children's Educational Attainment.

Jasmin WertzTerrie E MoffittJessica Agnew-BlaisLouise ArseneaultDaniel W BelskyDavid L CorcoranRenate HoutsTimothy MatthewsJoseph A PrinzLeah S Richmond-RakerdKaren SugdenBenjamin WilliamsAvshalom Caspi
Published in: Child development (2019)
This study tested implications of new genetic discoveries for understanding the association between parental investment and children's educational attainment. A novel design matched genetic data from 860 British mothers and their children with home-visit measures of parenting: the E-Risk Study. Three findings emerged. First, both mothers' and children's education-associated genetics, summarized in a genome-wide polygenic score, were associated with parenting-a gene-environment correlation. Second, accounting for genetic influences slightly reduced associations between parenting and children's attainment-indicating some genetic confounding. Third, mothers' genetics were associated with children's attainment over and above children's own genetics, via cognitively stimulating parenting-an environmentally mediated effect. Findings imply that, when interpreting parents' effects on children, environmentalists must consider genetic transmission, but geneticists must also consider environmental transmission.
Keyphrases
  • genome wide
  • young adults
  • copy number
  • gene expression
  • machine learning
  • dna methylation
  • risk assessment
  • climate change
  • electronic health record
  • cognitive decline
  • data analysis