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Recent advances to Neuroprotection: repurposing drugs against neuroinflammatory disorders.

Wishah BilalMuhammad Babar KhawarAli AfzalArshia NaseerSyeda Eisha HamidSara ShahzamanFareeha Qamar
Published in: Molecular biology reports (2023)
Cell death is a natural mechanism for biological clearance for the maintenance of homeostasis in a dynamic microenvironment of the central nervous system. Stress and various factors can lead to imbalance between cellular genesis and cell death leading to dysfunctionality and a number of neuropathological disorders. Drug repurposing can help bypass development time and cost. A complete understanding of drug actions and neuroinflammatory pathways can lead to effective control of neurodegenerative disorders. This review covers recent advances in various neuroinflammatory pathways understanding, biomarkers, and drug repurposing for neuroprotection.
Keyphrases
  • cell death
  • brain injury
  • drug induced
  • stem cells
  • cell cycle arrest
  • cerebral ischemia
  • emergency department