Insulin Therapy on Bone Macroscopic, Microarchitecture, and Mechanical Properties of Tibia in Diabetic Rats.

Pedro Henrique Justino Oliveira LimirioNilson Ferreira De Oliveira NetoJessyca Figueira VenâncioCamila LinharesPriscilla Barbosa Ferreira SoaresPaula Dechichi

Published in: Current diabetes reviews (2024)

T1DM reduces bone growth and mechanical strength. Insulin therapy in diabetic rats improved bone growth and fracture resistance, making diabetic bone similar to normoglycemic animals.

Keyphrases

diabetic rats
bone mineral density
oxidative stress
type diabetes
soft tissue
bone loss
glycemic control
body composition
mesenchymal stem cells
skeletal muscle
bone marrow
cell therapy
smoking cessation