Bone biology-related gingival transcriptome in ageing and periodontitis in non-human primates.

Subramanya N PandruvadaOctavio A GonzalezSreenatha KirakoduSudha GudhimellaArnold J StrombergJeffrey L EbersoleLuis OrracaJanis Gonzalez-MartinezMichael J NovakSarandeep S Huja

Published in: Journal of clinical periodontology (2016)

A pro-osteoclastogenic gingival transcriptome is associated with periodontitis irrespective of age; however; a greater bone-destructive molecular environment is associated with ageing in healthy tissues.

Keyphrases

gene expression
bone mineral density
rna seq
single cell
endothelial cells
genome wide
soft tissue
bone loss
bone regeneration
postmenopausal women
induced pluripotent stem cells
dna methylation