Identification of bifurcation transitions in biological regulatory networks using Answer-Set Programming.
Louis Fippo FitimeOlivier RouxCarito GuziolowskiLoïc PaulevéPublished in: Algorithms for molecular biology : AMB (2017)
Our method allows a formal and scalable identification of transitions which are responsible for the lost of capability to reach a given state. It can be applied to any asynchronous automata networks, which encompass Boolean and multi-valued models. An implementation is provided as part of the Pint software, available at http://loicpauleve.name/pint.