P2X3 Receptor in Primary Afferent Neurons Mediates the Relief of Visceral Hypersensitivity by Electroacupuncture in an Irritable Bowel Syndrome Rat Model.

Fang ZhangZhe MaZhijun WengMin ZhaoHandan ZhengLuyi WuYuan LuChunhui BaoYanan LiuHui-Rong Liu Huan-Gan Wu

Published in: Gastroenterology research and practice (2020)

EA can regulate the P2X3 receptor protein and mRNA expression levels in the colon and related DRG of IBS rats with visceral pain and then regulate the excitatory properties of DRG neurons.

Keyphrases

irritable bowel syndrome
spinal cord
neuropathic pain
insulin resistance
chronic pain
binding protein
drug induced
type diabetes
spinal cord injury
metabolic syndrome
cerebral ischemia
small molecule
blood brain barrier