Relationship between GABRB2 gene polymorphisms and schizophrenia susceptibility: a case-control study and in silico analyses.

Milad Heidari Nia Ramin Saravani Ramin Saravani Shekoufeh Mirinejad Danial Jahantigh Mansour Shakiba

Published in: The International journal of neuroscience (2020)

We found that intronic GABRB2 polymorphisms were associated with SCZ risk in a sample of the Iranian population. These findings provided proof of concept for the involvement of the GABAergic neurotransmission system in SCZ development. These observations should be validated across other ethnicities and clinical subtypes.

Keyphrases

bipolar disorder
molecular docking