Tenofovir-Diphosphate in Dried Blood Spots vs Tenofovir in Urine/Plasma for Oral Preexposure Prophylaxis Adherence Monitoring.

Xin NiuRachel W KubiakOraphan SiriprakaisilVirat KlinbuyaemPra Ornsuda SukrakanchanaRatchada CresseyHideaki OkochiMonica GandhiTim R CresseyPaul K Drain

Published in: Open forum infectious diseases (2022)

TFV-DP levels in DBS provide valuable insight into both dosing recency and cumulative doses from variable adherence patterns. Our observed benchmark TFV-DP concentrations were slightly higher than prior predicted estimates based on convenience samples.

Keyphrases

antiretroviral therapy
deep brain stimulation
men who have sex with men
glycemic control
type diabetes