Predictors of valproic acid steady-state serum levels in adult and pediatric psychiatric inpatients: a comparative analysis.

Matan AvrahamiTimur LiwinskiZafrir EcksteinMiriam PeskinPolina PerlmanJan SarlonUndine E LangDaniela AmitalAbraham Weizman

Published in: Psychopharmacology (2024)

This study highlights the utility of population-specific pharmacokinetic data for VPA in psychiatric populations. Age, gender, and co-administration of diazepam were identified as predictors of VPA levels. Further research is warranted to establish additional predictors and optimize the precision application of VPA in psychiatric patients.

Keyphrases

mental health
end stage renal disease
newly diagnosed
chronic kidney disease
peritoneal dialysis
electronic health record
big data
young adults
deep learning
childhood cancer