Epilepsy surgery below the age of 5 years: Are we still in time to preserve developmental and intellectual functions?

Simona Cappelletti Cinzia Correale Mattia Mercier Giusy Carfi Pavia Chiara Falamesca De Benedictis Alessandro Carlo Efisio Marras Chiara Quintavalle Concetta Luisi Chiara Pepi Daniela Chiarello Federico Vigevano Luca De Palma Nicola Specchio

Published in: Epilepsia open (2024)

This retrospective study, conducted at the Bambino Gesù Children Hospital in Italy, reports neuropsychological and developmental and/or cognitive data for children undergoing early epilepsy surgery (before the age of 5). It found that children with lower developmental or cognitive profiles gained the highest scores on post-operative neuropsychological evaluations. This study provides information on the potential benefits of early surgery in shortening the duration of epilepsy, preventing or arresting deterioration, and enhancing plasticity and recovery.

Keyphrases

minimally invasive
coronary artery bypass
young adults
surgical site infection
mild cognitive impairment
healthcare
emergency department
electronic health record
big data
risk assessment
adverse drug
machine learning
atrial fibrillation
data analysis