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Cryogenic electron tomography reveals novel structures in the apical complex of Plasmodium falciparum .

Stella Y SunYechiel ShaiGrigore D PintilieChi Yong KimSophia R StaggersMichael F SchmidElizabeth S EganWah ChiuJohn C Boothroyd
Published in: mBio (2024)
. These discoveries shed light on the essential and conserved elements of the invasion machinery used by these pathogens. Moreover, the research provides a foundation for understanding the molecular mechanisms underlying parasite-host interactions, potentially informing strategies for combating diseases caused by apicomplexan parasites.
Keyphrases
  • plasmodium falciparum
  • electron microscopy
  • cell migration
  • gram negative
  • transcription factor
  • high resolution
  • antimicrobial resistance
  • single molecule
  • electron transfer