Comparison of the efficacy and safety of quetiapine and lithium for bipolar depression: A systematic review and meta-analysis of randomized controlled trials.

Masaya Ogasawara Masahiro Takeshima Yuichi EsakiYoshiyuki KanekoTomohiro Utsumi Yumi AokiNorio WatanabeMasahiro Suzuki Yoshikazu Takaesu

Published in: Neuropsychopharmacology reports (2022)

Although this study found no differences in the efficacy and safety of quetiapine and lithium for bipolar depression, a comprehensive comparison of antipsychotics and mood stabilizers was not performed. Further studies are needed to clarify which of these, not just quetiapine and lithium, is more useful for bipolar depression.

Keyphrases

bipolar disorder
sleep quality
depressive symptoms
systematic review
clinical evaluation