CD39 positive regulatory T cell frequency as a biomarker of treatment response to methotrexate in rheumatoid arthritis.

Vikas GuptaShobhita KatiyarAnkita SinghShubhini A Saraf Aggarwal Amita

Published in: International journal of rheumatic diseases (2018)

Higher frequencies of CD39+ Tregs and CD4+ CD25+ CD39+ cells in the peripheral blood are associated with response to MTX in RA and hence, these could be considered as potential biomarkers for prediction of response to MTX treatment.

Keyphrases

rheumatoid arthritis
peripheral blood
disease activity
induced apoptosis
nk cells
transcription factor
ankylosing spondylitis
high dose
systemic lupus erythematosus
cell proliferation
replacement therapy