Gendered effects on inflammation reaction and outcome of COVID-19 patients in Wuhan.
Lu QinXiaochen LiJing ShiMuqing YuKe WangYu TaoYing ZhouMin ZhouShuyun XuBo WuZhenyu YangCong ZhangJunqing YueChongsheng ChengXiansheng LiuMin XiePublished in: Journal of medical virology (2020)
Sex, age, and comorbidity are critical risk factors for mortality of COVID-19. Excess innate immunity and proinflammation activity, and deficiency in adaptive immunity response promote males, especially elder males, to develop a cytokine storm, causing potential acute respiratory distressed syndrome, multiple organ failure and decease.
Keyphrases
- coronavirus disease
- sars cov
- liver failure
- oxidative stress
- respiratory failure
- cardiovascular events
- respiratory syndrome coronavirus
- drug induced
- aortic dissection
- case report
- risk factors
- human health
- replacement therapy
- cardiovascular disease
- respiratory tract
- risk assessment
- acute respiratory distress syndrome
- mechanical ventilation