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Psoriasis After Exposure to Angiotensin-Converting Enzyme Inhibitors: French Pharmacovigilance Data and Review of the Literature.

Brahim AzzouzAurore MorelLukshe KanagaratnamEmmanuelle HerlemThierry Trenque
Published in: Drug safety (2020)
We found a statistically significant association between psoriasis and ACEI, which constitutes a potential safety signal. The risk of psoriasis is a class effect, time to onset is less than 1 year, and outcome is favorable after ACEI discontinuation. Psoriasis should be mentioned in the SmPCs of all ACEIs, and healthcare professionals should be informed about this risk.
Keyphrases
  • angiotensin converting enzyme
  • angiotensin ii
  • atopic dermatitis
  • emergency department
  • drug induced
  • human health