The adjunctive effect of rhBMP-2 on the regeneration of peri-implant bone defects after experimental peri-implantitis.

(a) The addition of rhBMP2 to a bovine xenograft/collagen vehicle carrier failed to provide a significant added value in terms of bone regeneration or re-osseointegration, (b) partial re-osseointegration of a previously contaminated surface was achieved, although (c) a complete defect resolution and re-osseointegration to the level previous to the induction of the disease failed to occur in any of the treatment groups.