Bacterial Vaginosis and Post-Operative Pelvic Infections.
Afroditi ZiogouEleftherios ZiogosIlias GiannakodimosAlexios GiannakodimosStavros SifakisPetros IoannouSotirios TsiodrasPublished in: Healthcare (Basel, Switzerland) (2023)
Bacterial vaginosis (BV) represents a condition in which the normal protective Lactobacilli, especially those that produce H 2 O 2 , are replaced by high quantities of facultative anaerobes, leading to gynecologic and obstetric post-operative complications. BV is an important cause of obstetric and gynecological adverse sequelae and it could lead to an increased risk of contracting sexually transmitted infections such as gonorrhea, genital herpes, Chlamydia , Trichomonas , and human immunodeficiency virus. Herein, we reviewed bacterial vaginosis and its association with post-operative pelvic infections. In Obstetrics, BV has been associated with increased risk of preterm delivery, first-trimester miscarriage in women undergoing in vitro fertilization, preterm premature rupture of membranes, chorioamnionitis, amniotic fluid infections, postpartum and postabortal endomyometritis as well as postabortal pelvic inflammatory disease (PID). In gynecology, BV increases the risk of post-hysterectomy infections such as vaginal cuff cellulitis, pelvic cellulitis, pelvic abscess, and PID. BV is often asymptomatic, can resolve spontaneously, and often relapses with or without treatment. The American College of Obstetricians and Gynecologists recommends testing for BV in women having an increased risk for preterm delivery. Women with symptoms should be evaluated and treated. Women with BV undergoing gynecological surgeries must be treated to reduce the frequency of post-operative pelvic infections. Metronidazole and clindamycin are the mainstays of therapy. Currently, there is no consensus on pre-surgery screening for BV; decisions are made on a case-by-case basis.
Keyphrases
- lps induced
- lipopolysaccharide induced
- rectal cancer
- human immunodeficiency virus
- inflammatory response
- pregnant women
- polycystic ovary syndrome
- preterm birth
- hepatitis c virus
- low birth weight
- type diabetes
- hiv infected
- minimally invasive
- stem cells
- hiv aids
- risk factors
- gestational age
- preterm infants
- metabolic syndrome
- pregnancy outcomes
- skeletal muscle
- cell therapy
- emergency department
- coronary artery disease
- mesenchymal stem cells
- electronic health record
- combination therapy
- adverse drug