Co-treatment of Naringenin and Ketoprofen-RGD Suppresses Cell Proliferation via Calmodulin/PDE/cAMP/PKA Axis Pathway in Leukemia and Ovarian Cancer Cells.

Havva AfshariShokoofe NooriBahareh ShokriAfshin Zarghi

Published in: Iranian journal of pharmaceutical research : IJPR (2023)

This study indicated for the first time that combining ketoprofen-RGD and Nar can be a promising anti-inflammatory therapeutic regimen for treating leukemia and ovarian cancer.

Keyphrases

cell proliferation
acute myeloid leukemia
anti inflammatory
bone marrow
protein kinase
signaling pathway
cell cycle
pi k akt
replacement therapy