An immune, stroma, and epithelial-mesenchymal transition-related signature for predicting recurrence and chemotherapy benefit in stage II-III colorectal cancer.

Du CaiWei WangMin-Er ZhongDejun FanXuanhui LiuCheng-Hang LiZe-Ping HuangQiqi ZhuMin-Yi LvChuling HuXin DuanXiao-Jian WuFeng Gao

Published in: Cancer medicine (2023)

We proposed an ISE signature for robustly predicting the recurrence of stage II/III CRC and help treatment decision by identifying patients who will not benefit from current standard treatment.

Keyphrases

epithelial mesenchymal transition
squamous cell carcinoma
combination therapy
radiation therapy
locally advanced
decision making