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Stress less: Viral mastery of the RNA G-quadruplex.

Sheila GonzalezMaria G NovalJessica M Tucker
Published in: Cell host & microbe (2024)
RNA G-quadruplexes are dynamically regulated during stress and infection. In this issue of Cell Host & Microbe, Schult et al. 1 demonstrate that an RNA G-quadruplex conserved across orthoflaviviruses binds hnRNPH1 to mitigate the host stress response, highlighting the potential of this dynamic proviral RNA structure as a pan-flaviviral target.
Keyphrases
  • nucleic acid
  • transcription factor
  • sars cov
  • single cell
  • stem cells
  • risk assessment
  • cell therapy
  • stress induced
  • heat stress