Angiopoietin-2 as a predictor of acute kidney injury in critically ill patients and association with ARDS.

Camila Barbosa AraújoFernanda Macedo de Oliveira NevesDaniele Ferreira de FreitasBianca Fernandes Távora ArrudaLeonardo José Monteiro de Macêdo FilhoVivian Brito SallesGdayllon Cavalcante MenesesAlice Maria Costa MartinsAlexandre Braga Libório

Published in: Respirology (Carlton, Vic.) (2019)

AGPT2 and AGPT2/AGPT1 ratio are associated with severe AKI and there was only a need of renal replacement therapy (RRT) in patients with or at risk of ARDS, not in other critically ill patients. Adding AGPT2 to a clinical model resulted in a significant improvement in the capacity to predict severe AKI specifically in ARDS patients.

Keyphrases

acute kidney injury
acute respiratory distress syndrome
extracorporeal membrane oxygenation
mechanical ventilation
end stage renal disease
ejection fraction
newly diagnosed
early onset
chronic kidney disease
prognostic factors
peritoneal dialysis
patient reported outcomes
intensive care unit
drug induced