Helicobacter pylori Seropositivity, ABO Blood Type, and Pancreatic Cancer Risk from 5 Prospective Cohorts.
Alice A LeeQiao-Li WangJihye KimAna BabicXuehong ZhangKimberly PerezKimmie NgJonathan NowakNader RifazzzzzzzzgiHoward D SessoJulie E BuringGarnet L AndersonJean Wactawski-WendeRobert WallaceJoAnn E MansonEdward L GiovannucciMeir J StampferPeter KraftCharles S FuchsChen YuanBrian M WolpinPublished in: Clinical and translational gastroenterology (2023)
In this nested case-control study, history of H. pylori infection as determined by H. pylori antibody serology was not associated with pancreatic cancer risk, regardless of CagA virulence factor status. The elevated risk associated with non-O blood type was consistent in those with or without H. pylori seropositivity.