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Association of intraoperative dexmedetomidine use with postoperative hypotension in unilateral hip and knee arthroplasties: a historical cohort study.

Stephen Su YangCharles GelinasEdmund YimMandy M J LiKenneth KardashMichelle ZhangJed Lipes
Published in: Canadian journal of anaesthesia = Journal canadien d'anesthesie (2022)
In this historical cohort study, dexmedetomidine was a strong risk factor for postoperative hypotension in total hip or knee arthroplasty patients. Dexmedetomidine, and particularly at high cumulative doses above 50 μg, should be administered judiciously in high-risk surgical patients to minimize the risk of postoperative hypotension.
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