A new role for circulating T follicular helper cells in humoral response to anti-PD-1 therapy.

Santiago Sánchez-AlonsoGiulia Setti-JerezMontserrat ArroyoTathiana HernándezMª Inmaculada MartosJose Miguel Sánchez-TorresRamon ColomerAlmudena R RamiroArantzazu Alfranca

Published in: Journal for immunotherapy of cancer (2021)

These findings unveil a novel mechanism of action for anti-PD-1 therapy and provide new targets for optimization of current therapies against lung cancer.

Keyphrases

induced apoptosis
immune response
cell cycle arrest
stem cells
dendritic cells
cell therapy