Myocardial Milieu Favors Local Differentiation of Regulatory T Cells.
Murilo DelgoboEmil WeißDiyaaElDin AshourLeon RichterLisa PopiolkowskiPanagiota ArampatziVerena StanglAnahi-Paula Arias-LozaEncarnita Mariotti-FerrandizPeter P RainerAntoine-Emmanuel SalibaBurkhard LudewigUlrich HofmannStefan FrantzGustavo Campos RamosPublished in: Circulation research (2023)
These findings provide novel evidence that the heart and its draining lymph nodes actively shape local immune responses by promoting the differentiation of antigen-specific Tregs poised with suppressive function.