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Natriuretic peptides relax human intrarenal arteries through natriuretic peptide receptor type-A recapitulated by soluble guanylyl cyclase agonists.

Andreas FreesKasper Bostlund AssersenMia JensenPernille B L HansenPaul M VanhoutteKirsten MadsenAnna FederleinLars LundAnja ToftBoye L Jensen
Published in: Acta physiologica (Oxford, England) (2020)
Activation of transmembrane NPR-A and soluble guanylyl cyclase relax human preglomerular arteries similarly to phosphodiestase-5 inhibition. The human renal arterial bed relaxes in response to cGMP pathway.
Keyphrases
  • endothelial cells
  • induced pluripotent stem cells
  • blood flow