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Polymorphisms in solute carrier genes (SLC19A1, SLCO1B1, and SLCO1B3) predicts survival and toxicity in North Indian lung cancer patients undergoing platinum-based doublet chemotherapy.

Parul SharmaNavneet SinghSiddharth Sharma
Published in: Journal of clinical pharmacy and therapeutics (2022)
Our findings imply that Solute Carrier gene polymorphisms modulate the overall survival in lung cancer patients undergoing platin-based doublet chemotherapy, also these polymorphisms have a modifying impact on the associated adverse events/toxicity.
Keyphrases
  • patients undergoing
  • locally advanced
  • oxidative stress
  • free survival
  • genome wide
  • squamous cell carcinoma
  • radiation therapy
  • chemotherapy induced
  • gene expression
  • dna methylation
  • oxide nanoparticles