Enoxaparin attenuates pyrrolizidine alkaloids-induced hepatic sinusoidal obstruction syndrome by inhibiting oncostatin M expression.

Hongyu XiangChang LiuZhuanglong XiaoLi DuNing WeiFang LiuYuhu Song

Published in: Liver international : official journal of the International Association for the Study of the Liver (2022)

LMWH attenuated severe liver injury in patients with PAs-Induced HSOS and animal models of MCT-induced HSOS, which provides a rationale for the application of anticoagulation therapy.

Keyphrases

drug induced
liver injury
high glucose
diabetic rats
venous thromboembolism
clinical trial
atrial fibrillation
endothelial cells
bone marrow