Asthma in elderly is characterized by increased sputum neutrophils, lower airway caliber variability and air trapping.
Florence SchleichS GraffF GuissardM HenketV PaulusR LouisPublished in: Respiratory research (2021)
Our study highlights that asthmatics older than 70 years old have higher bronchial neutrophilic inflammation, a poorer lung function, signs of air trapping and lower airway variability. The role of immunosenescence inducing chronic low-grade inflammation in this asthma subtype remains to be elucidated.