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Asthma in elderly is characterized by increased sputum neutrophils, lower airway caliber variability and air trapping.

Florence SchleichS GraffF GuissardM HenketV PaulusR Louis
Published in: Respiratory research (2021)
Our study highlights that asthmatics older than 70 years old have higher bronchial neutrophilic inflammation, a poorer lung function, signs of air trapping and lower airway variability. The role of immunosenescence inducing chronic low-grade inflammation in this asthma subtype remains to be elucidated.
Keyphrases
  • lung function
  • low grade
  • cystic fibrosis
  • chronic obstructive pulmonary disease
  • air pollution
  • oxidative stress
  • high grade
  • middle aged
  • community dwelling
  • physical activity
  • drug induced