Functionalized Titanium Nanoparticles Induce Oxidative Stress and Cell Death in Human Skin Cells.

Patricia BrassolattiJoice Margareth de Almeida RodolphoKrissia Franco de GodoyCynthia Aparecida de CastroGenoveva Lourdes Flores LunaBruna Dias de Lima FragelliMatheus PedrinoMarcelo AssisMarcel Nani LeiteJuliana Cancino-BernardiCarlos SpeglichMarco Andrey FradeFernanda de Freitas Anibal

Published in: International journal of nanomedicine (2022)

Thus, it is possible to conclude that the cytotoxicity mechanism differs according to the cell type evaluated, with HDFn being the most sensitive line in this case, and this mechanism can be defined in a dose and time dependent manner, since the highest concentrations also triggered death cell.

Keyphrases

cell death
cell cycle arrest
induced apoptosis
oxidative stress
single cell
endoplasmic reticulum stress
cell therapy
dna damage
signaling pathway
quantum dots
ischemia reperfusion injury
pi k akt
stem cells
molecularly imprinted
cell proliferation
heat shock