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Regulation of osteoclastogenesis by mast cell in rheumatoid arthritis.

Kyoung-Woon KimBo-Mi KimJi-Yeon WonHong-Ki MinKyung-Ann LeeSang-Heon LeeHae-Rim Kim
Published in: Arthritis research & therapy (2021)
IL-33 increased inflammatory and tissue-destructive cytokines by activation of mast cells. Mast cells stimulated osteoclast differentiation in monocytes. Mast cells could stimulate osteoclastogenesis indirectly through production of tissue-destructive cytokines and directly through stimulation of osteoclast precursors.
Keyphrases
  • bone loss
  • rheumatoid arthritis
  • lps induced
  • oxidative stress
  • dendritic cells
  • disease activity
  • ankylosing spondylitis
  • peripheral blood
  • systemic lupus erythematosus
  • inflammatory response
  • immune response