Sex differences in the MB49 syngeneic, murine model of bladder cancer.
Shai White-GilbertsonMegan DavisChristina Voelkel-JohnsonLaura M KasmanPublished in: Bladder (San Francisco, Calif.) (2016)
The MB49 murine model of bladder cancer reproduced some aspects of the sex differences observed in humans. Our results suggest that testosterone may stimulate MB49 cell proliferation, which may explain the more rapid MB49 tumor growth observed in male mice.