Characterization of the rhesus macaque (Macaca mulatta) scrub typhus model: Susceptibility to intradermal challenge with the human pathogen Orientia tsutsugamushi Karp.

Piyanate SunyakumthornSuwit J SomponpunRawiwan Im-ErbsinTippawan AnantatatKemajittra JenjaroenSusanna J DunachieEric D LombardiniRobin L BurkeStuart D BlacksellJames W JonesCarl J MasonAllen L RichardsNicholas P J DayDaniel Henry Paris

Published in: PLoS neglected tropical diseases (2018)

These data show the potential of using rhesus macaques as a scrub typhus model, for evaluation of correlates of protection in both natural and vaccine induced immunity, and support the evaluation of future vaccine candidates against scrub typhus.

Keyphrases

endothelial cells
high glucose
electronic health record
diabetic rats
current status
machine learning
risk assessment
induced pluripotent stem cells
oxidative stress